Talele, Tanaji: search on Z-Library

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1

The “Cyclopropyl Fragment” is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules

Talele, Tanaji T

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 9.33 MB

english, 2016

2

Successful Applications of Computer Aided Drug Discovery: Moving Drugs from Concept to the Clinic

Talele, Tanaji, Khedkar, Santosh, Rigby, Alan

Journal:

Current Topics in Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 422 KB

english, 2010

3

Discovery and Structure–Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2 H )-one-7-carboxamide Derivatives as Poly(ADP-ribose)polymerase-1 Inhibitors

Patel, Maulik R., Bhatt, Aaditya, Steffen, Jamin D., Chergui, Adel, Murai, Junko, Pommier, Yves, Pascal, John M., Trombetta, Louis D., Fronczek, Frank R., Talele, Tanaji T.

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 5.58 MB

english, 2014

4

3D QSAR studies of 1,3,4-benzotriazepine derivatives as CCK2 receptor antagonists

Kirandeep Kaur, Tanaji T. Talele

Journal:

Journal of Molecular Graphics and Modelling

Year:

2008

Language:

english

File:

PDF, 734 KB

english, 2008

5

The synthesis and SAR study of phenylalanine-derived (Z)-5-arylmethylidene rhodanines as anti-methicillin-resistant Staphylococcus aureus (MRSA) compounds

Patel, Bhargav A., Ashby, Charles R., Hardej, Diane, Talele, Tanaji T.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 532 KB

english, 2013

6

AST1306, a potent EGFR inhibitor, antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance

Zhang, Hui, Wang, Yi-Jun, Zhang, Yun-Kai, Wang, De-Shen, Kathawala, Rishil J., Patel, Atish, Talele, Tanaji T., Chen, Zhe-Sheng, Fu, Li-Wu

Journal:

Year:

2014

Language:

english

File:

PDF, 1.24 MB

english, 2014

7

Discovery of conjugated thiazolidinone-thiadiazole scaffold as anti-dengue virus polymerase inhibitors

Manvar, Dinesh, Küçükgüzel, İlkay, Erensoy, Gizem, Tatar, Esra, Deryabaşoğulları, Gökhan, Reddy, Haarika, Talele, Tanaji T., Cevik, Ozge, Kaushik-Basu, Neerja

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 839 KB

english, 2015

8

Opportunities for Tapping into Three-Dimensional Chemical Space Through a Quaternary Carbon

Talele, Tanaji T

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 1.19 MB

2020

9

Some Hydrazones of 2-Aroylamino-3-methylbutanohydrazide: Synthesis, Molecular Modeling Studies, and Identification as Stereoselective Inhibitors of HIV-1

Tatar, Esra, Küçükgüzel, İlkay, Daelemans, Dirk, Talele, Tanaji T., Kaushik-Basu, Neerja, De Clercq, Erik, Pannecouque, Christophe

Journal:

Archiv der Pharmazie

Year:

2013

Language:

english

File:

PDF, 358 KB

english, 2013

10

The molluscum contagiosum virus death effector domain containing protein MC160 RxDL motifs are not required for its known viral immune evasion functions

Beaury, Michael, Velagapudi, Uday Kiran, Weber, Sarah, Soto, Cassandra, Talele, Tanaji T., Nichols, Daniel Brian

Journal:

Year:

2017

Language:

english

File:

PDF, 4.72 MB

english, 2017

11

Design and Synthesis of Poly(ADP-ribose) polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity

Velagapudi, Uday Kiran, Langelier, Marie-France, Delgado-Martin, Cristina, Diolaiti, Morgan E, Bakker, Sietske, Ashworth, Alan, Patel, Bhargav A, Shao, Xuwei, Pascal, John M., Talele, Tanaji T

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 1.18 MB

english, 2019

12

Pharmacophore Modeling of Nilotinib as an Inhibitor of ATP-Binding Cassette Drug Transporters and BCR-ABL Kinase Using a Three-Dimensional Quantitative Structure–Activity Relationship Approach

Shukla, Suneet, Kouanda, Abdul, Silverton, Latoya, Talele, Tanaji T., Ambudkar, Suresh V.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

13

ARRY-334543 Reverses Multidrug Resistance by Antagonizing the Activity of ATP-Binding Cassette Subfamily G Member 2

Wang, De-Shen, Patel, Atish, Sim, Hong-May, Zhang, Yun-Kai, Wang, Yi-Jun, Kathawala, Rishil J., Zhang, Hui, Talele, Tanaji T., Ambudkar, Suresh V., Xu, Rui-Hua, Chen, Zhe-Sheng

Journal:

Journal of Cellular Biochemistry

Year:

2014

Language:

english

File:

PDF, 1.22 MB

english, 2014

14

The synthesis of phenylalanine-derived C5-substituted rhodanines and their activity against selected methicillin-resistant Staphylococcus aureus (MRSA) strains

Diane Hardej, Charles R. Ashby Jr., Nikhil S. Khadtare, Shridhar S. Kulkarni, Satyakam Singh, Tanaji T. Talele

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 237 KB

english, 2010

15

Insertion of a peptide from MuLV RT into the connection subdomain of HIV-1 RT results in a functionally active chimeric enzyme in monomeric conformation

Pradeep K. Pandey, Neerja Kaushik, Tanaji T. Talele, Prem N.S. Yadav, Virendra N. Pandey

Journal:

Molecular and Cellular Biochemistry

Year:

2001

Language:

english

File:

PDF, 333 KB

english, 2001

16

Nilotinib potentiates anticancer drug sensitivity in murine ABCB1-, ABCG2-, and ABCC10-multidrug resistance xenograft models

Amit K. Tiwari, Kamlesh Sodani, Chun-ling Dai, Alaa H. Abuznait, Satyakam Singh, Zhi-Jie Xiao, Atish Patel, Tanaji T. Talele, Liwu Fu, Amal Kaddoumi, James M. Gallo, Zhe-Sheng Chen

Journal:

Year:

2013

Language:

english

File:

PDF, 1.55 MB

english, 2013

17

Discovery of new scaffolds for rational design of HCV NS5B polymerase inhibitors

Golub, Andriy G., Gurukumar, K.R., Basu, Amartya, Bdzhola, Volodymyr G., Bilokin, Yaroslav, Yarmoluk, Sergiy M., Lee, Jin-Ching, Talele, Tanaji T., Nichols, Daniel B., Kaushik-Basu, Neerja

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 776 KB

english, 2012

18

Enhancing Chemosensitivity in ABCB1- and ABCG2-Overexpressing Cells and Cancer Stem-like Cells by An Aurora Kinase Inhibitor CCT129202

Cheng, Chao, Liu, Zhen-guo, Zhang, Hui, Xie, Jing-dun, Chen, Xing-gui, Zhao, Xiao-qin, Wang, Fang, Liang, Yong-ju, Chen, Li-kun, Singh, Satyakam, Chen, Jun-jiang, Talele, Tanaji T., Chen, Zhe-sheng, Z

Journal:

Molecular Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 3.16 MB

english, 2012

19

The β7−β8 Loop of the p51 Subunit in the Heterodimeric (p66/p51) Human Immunodeficiency Virus Type 1 Reverse Transcriptase Is Essential for the Catalytic Function of the p66 Subunit †

Pandey, Pradeep K., Kaushik, Neerja, Talele, Tanaji T., Yadav, Prem N. S., Pandey, Virendra N.

Journal:

Year:

2001

Language:

english

File:

PDF, 373 KB

english, 2001

20

In Vitro Antibacterial Activity of Rhodanine Derivatives against Pathogenic Clinical Isolates

AbdelKhalek, Ahmed, Ashby, Charles R., Patel, Bhargav A., Talele, Tanaji T., Seleem, Mohamed N., Chang, Yung-Fu

Journal:

Year:

2016

Language:

english

File:

PDF, 1.67 MB

english, 2016

21

Saracatinib (AZD0530) is a potent modulator of ABCB1-mediated multidrug resistance in vitro and in vivo

Ke-Jun Liu, Jie-Hua He, Xiao-Dong Su, Hong-May Sim, Jing-Dun Xie, Xing-Gui Chen, Fang Wang, Yong-Ju Liang, Satyakam Singh, Kamlesh Sodani, Tanaji T. Talele, Suresh V. Ambudkar, Zhe-Sheng Chen, Hai-Yin

Journal:

International Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 631 KB

english, 2012

22

Design and Synthesis of N-Substituted Indazole-3-Carboxamides as Poly(ADP-ribose)polymerase-1 (PARP-1) Inhibitors

Maulik R. Patel, Kashyap G. Pandya, Cesar A. Lau-Cam, Satyakam Singh, Maria A. Pino, Blase Billack, Kurt Degenhardt, Tanaji T. Talele

Journal:

Chemical Biology & Drug Design

Year:

2012

Language:

english

File:

PDF, 261 KB

english, 2012

23

Design, Synthesis, and Evaluation of 2-(arylsulfonyl)oxiranes as Cell-permeable Covalent Inhibitors of Protein Tyrosine Phosphatases

Dibyendu Dana, Tirtha K. Das, Ish Kumar, Anibal R. Davalos, Kevin J. Mark, Daryl Ramai, Emmanuel J. Chang, Tanaji T. Talele, Sanjai Kumar

Journal:

Chemical Biology & Drug Design

Year:

2012

Language:

english

File:

PDF, 269 KB

english, 2012

24

Novel 4-Thiazolidinones as Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA Polymerase

Çakır, Gizem, Küçükgüzel, İlkay, Guhamazumder, Rupa, Tatar, Esra, Manvar, Dinesh, Basu, Amartya, Patel, Bhargav A., Zia, Javairia, Talele, Tanaji T., Kaushik-Basu, Neerja

Journal:

Archiv der Pharmazie

Year:

2015

Language:

english

File:

PDF, 881 KB

english, 2015

25

Role of Glutamine 151 of Human Immunodeficiency Virus Type-1 Reverse Transcriptase in Substrate Selection As Assessed by Site-Directed Mutagenesis †

Kaushik, Neerja, Talele, Tanaji T., Pandey, Pradeep K., Harris, Dylan, Yadav, Prem N. S., Pandey, Virendra N.

Journal:

Year:

2000

Language:

english

File:

PDF, 238 KB

english, 2000

26

Lamellarin O, a Pyrrole Alkaloid from an Australian Marine Sponge, Ianthella sp., Reverses BCRP Mediated Drug Resistance in Cancer Cells

Huang, Xiao-Cong, Xiao, Xue, Zhang, Yun-Kai, Talele, Tanaji, Salim, Angela, Chen, Zhe-Sheng, Capon, Robert

Journal:

Year:

2014

Language:

english

File:

PDF, 1.23 MB

english, 2014

27

Synthesis and SAR optimization of quinazolin-4(3H)-ones as poly(ADP-ribose)polymerase-1 inhibitors

Shridhar S. Kulkarni, Satyakam Singh, Janki R. Shah, Woon-Kai Low, Tanaji T. Talele

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 834 KB

english, 2012

28

Multiple Allosteric Pockets of HCV NS5B Polymerase and its Inhibitors: A Structure Based Insight

Journal:

Current Bioactive Compounds

Year:

2008

Language:

english

File:

PDF, 1.38 MB

english, 2008

29

Revisiting Prochirality

Ochs, Raymond S., Talele, Tanaji T.

Journal:

Year:

2019

File:

PDF, 3.13 MB

2019

30

Synthesis and SAR optimization of diketo acid pharmacophore for HCV NS5B polymerase inhibition

Aaditya Bhatt, K.R. Gurukumar, Amartya Basu, Maulik R. Patel, Neerja Kaushik-Basu, Tanaji T. Talele

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 381 KB

english, 2011

31

CoMFA and CoMSIA Studies on 1,3-Bis(benzylidene)-3,4-dihydro-1 H -naphthalen-2-one, 2,6-Bis(benzylidene)cyclohexanone, and 3,5-Bis(benzylidene)-4-piperidone Series of Cytotoxic Compounds

Patel, Maulik R., Dimmock, Jonathan R., Talele, Tanaji T.

Journal:

Journal of Chemical Information and Modeling

Year:

2007

Language:

english

File:

PDF, 469 KB

english, 2007

32

Linsitinib (OSI-906) antagonizes ATP-binding cassette subfamily G member 2 and subfamily C member 10-mediated drug resistance

Zhang, Hui, Kathawala, Rishil J., Wang, Yi-Jun, Zhang, Yun-Kai, Patel, Atish, Shukla, Suneet, Robey, Robert W., Talele, Tanaji T., Ashby, Charles R., Ambudkar, Suresh V., Bates, Susan E., Fu, Li-Wu, C

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2014

Language:

english

File:

PDF, 1.94 MB

english, 2014

33

Telatinib reverses chemotherapeutic multidrug resistance mediated by ABCG2 efflux transporter in vitro and in vivo

Sodani, Kamlesh, Patel, Atish, Anreddy, Nagaraju, Singh, Satyakam, Yang, Dong-Hua, Kathawala, Rishil J., Kumar, Priyank, Talele, Tanaji T., Chen, Zhe-Sheng

Journal:

Biochemical Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.68 MB

english, 2014

34

Design and Synthesis of Human ABCB1 (P-Glycoprotein) Inhibitors by Peptide Coupling of Diverse Chemical Scaffolds on Carboxyl and Amino Termini of ( S )-Valine-Derived Thiazole Amino Acid

Singh, Satyakam, Prasad, Nagarajan Rajendra, Chufan, Eduardo E., Patel, Bhargav A., Wang, Yi-Jun, Chen, Zhe-Sheng, Ambudkar, Suresh V., Talele, Tanaji T.

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 3.25 MB

english, 2014

35

Characterization of Solid Dispersion of Itraconazole Prepared by Solubilization in Concentrated Aqueous Solutions of Weak Organic Acids and Drying

Parikh, Tapan, Sandhu, Harpreet K., Talele, Tanaji T., Serajuddin, Abu T. M.

Journal:

Pharmaceutical Research

Year:

2016

Language:

english

File:

PDF, 1.67 MB

english, 2016

36

Comprehensive Synthesis of Amino Acid-derived Thiazole Peptidomimetic Analogues to Understand Enigmatic Drug/Substrate-Binding Site of P-glycoprotein

Patel, Bhargav A., Abel, Biebele, Barbuti, Anna Maria, Velagapudi, Uday Kiran, Chen, Zhe-sheng, Ambudkar, Suresh V., Talele, Tanaji T

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.09 MB

english, 2017

37

Identification of novel PARP-1 inhibitors by structure-based virtual screening

Hannigan, Kevin, Kulkarni, Shridhar S., Bdzhola, Volodymyr G., Golub, Andriy G., Yarmoluk, Sergiy M., Talele, Tanaji T.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 408 KB

english, 2013

38

Introspection

Zhang, Hui, Kathawala, Rishil J., Wang, Yi-Jun, Zhang, Yun-Kai, Patel, Atish, Shukla, Suneet, Robey, Robert W., Talele, Tanaji T., Ashby, Charles R., Ambudkar, Suresh V., Bates, Susan E., Fu, Li-Wu, C

Journal:

NPG Neurologie - Psychiatrie - Gériatrie

Year:

2009

Language:

french

File:

PDF, 259 KB

french, 2009

39

ChemInform Abstract: Design, Synthesis and Determination of Antifungal Activity of 5(6)-Substituted Benzotriazoles.

Pallav D. Patel, Maulik R. Patel, Bela Kocsis, Erika Kocsis, Steven M. Graham, Andrew R. Warren, Stacia M. Nicholson, Blase Billack, Frank R. Fronczek, Tanaji T. Talele

Journal:

Year:

2010

Language:

english

File:

PDF, 23 KB

english, 2010

40

Editorial [Medicinal Chemistry of Novel Therapeutics (Guest Editor: Tanaji Talele)]

Journal:

Current Bioactive Compounds

Year:

2008

Language:

english

File:

PDF, 24 KB

english, 2008

41

ChemInform Abstract: The Synthesis of Phenylalanine-Derived C5-Substituted Rhodanines and Their Activity Against Selected Methicillin-Resistant Staphylococcus aureus (MRSA) Strains.

Diane Hardej, Charles R. Jr. Ashby, Nikhil S. Khadtare, Shridhar S. Kulkarni, Satyakam Singh, Tanaji T. Talele

Journal:

Year:

2011

Language:

english

File:

PDF, 26 KB

english, 2011

42

CoMSIA Study on Substituted Aryl Alkanoic Acid Analogs as GPR40 Agonists

Aaditya Bhatt, Pallav D. Patel, Maulik R. Patel, Satyakam Singh, Cesar A. Lau-Cam, Tanaji T. Talele

Journal:

Chemical Biology & Drug Design

Year:

2011

Language:

english

File:

PDF, 630 KB

english, 2011

43

Dual inhibition of Staphylococcus aureus DNA gyrase and topoisomerase IV activity by phenylalanine-derived (Z)-5-arylmethylidene rhodanines

Werner, Malela M., Patel, Bhargav A., Talele, Tanaji T., Ashby, Charles R., Li, Zhiyu, Zauhar, Randy J.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 4.90 MB

english, 2015

44

Thiazole-valine peptidomimetic (TTT-28) antagonizes multidrug resistance in vitro and in vivo by selectively inhibiting the efflux activity of ABCB1

Wang, Yi-Jun, Patel, Bhargav A., Anreddy, Nagaraju, Zhang, Yun-Kai, Zhang, Guan-Nan, Alqahtani, Saeed, Singh, Satyakam, Shukla, Suneet, Kaddoumi, Amal, Ambudkar, Suresh V., Talele, Tanaji T., Chen, Zh

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

45

Design and Synthesis of Poly(ADP-ribose) polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity

Velagapudi, Uday Kiran, Langelier, Marie-France, Delgado-Martin, Cristina, Diolaiti, Morgan E, Bakker, Sietske, Ashworth, Alan, Patel, Bhargav A, Shao, Xuwei, Pascal, John M., Talele, Tanaji T

Journal:

Journal of Medicinal Chemistry

Year:

2019

File:

PDF, 1.18 MB

2019

46

Synthesis of 2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide and 3-oxo-3,4-dihydrobenzo[b][1,4]oxazine-8-carboxamide derivatives as PARP1 inhibitors

Shao, Xuwei, Pak, Steven, Kiran Velagapudi, Uday, Gobbooru, Shruthi, Shilpa Kommaraju, Sai, Low, Woon-Kai, Subramaniam, Gopal, Kumar Pathak, Sanjai, Talele, Tanaji T.

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.64 MB

2020

47

Inhibition of dipeptidyl peptidase-IV (DPP-IV) by atorvastatin

Tony Taldone, S. William Zito, Tanaji T. Talele

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 313 KB

english, 2008

48

GW583340 and GW2974, human EGFR and HER-2 inhibitors, reverse ABCG2- and ABCB1-mediated drug resistance

Kamlesh Sodani, Amit K. Tiwari, Satyakam Singh, Atish Patel, Zhi-Jie Xiao, Jun-Jiang Chen, Yue-Li Sun, Tanaji T. Talele, Zhe-Sheng Chen

Journal:

Biochemical Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.00 MB

english, 2012

49

WHI-P154 enhances the chemotherapeutic effect of anticancer agents in ABCG2-overexpressing cells

Zhang, Hui, Zhang, Yun-Kai, Wang, Yi-Jun, Kathawala, Rishil J., Patel, Atish, Zhu, Hua, Sodani, Kamlesh, Talele, Tanaji T., Ambudkar, Suresh V., Chen, Zhe-Sheng, Fu, Li-Wu

Journal:

Year:

2014

Language:

english

File:

PDF, 1.79 MB

english, 2014

50

Natural Products-Inspired Use of the Gem-Dimethyl Group in Medicinal Chemistry

Talele, Tanaji T

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 11.44 MB

english, 2017

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